Quantitative measurement of cerebral physiology using respiratory-calibrated MRI
نویسندگان
چکیده
منابع مشابه
Simultaneous quantitative assessment of cerebral physiology using respiratory-calibrated MRI and near-infrared spectroscopy in healthy adults
BACKGROUND Functional near-infrared spectroscopy (fNIRS) and functional MRI (fMRI) are non-invasive techniques used to relate activity in different brain regions to certain tasks. Respiratory calibration of the blood oxygen level dependent (BOLD) signal, and combined fNIRS-fMRI approaches have been used to quantify physiological subcomponents giving rise to the BOLD signal. A comparison of abso...
متن کاملChanges in cerebral physiology with ageing assessed by respiratory-calibrated MRI
Purpose: Recently, respiratory-calibrated MRI methods capable of providing a non-invasive, quantitative assessment of cerebral physiology have been developed. Although differing slightly in detail, the aim of these methods is the same: to calibrate the MRI signal using a combination of hyperoxic and hypercapnic gas stimuli, and thereby allow quantification of brain energy metabolism and perfusi...
متن کاملQuantitative Measurement of Cerebral Oxygen Extraction Fraction Using MRI in Patients with MELAS
OBJECTIVE To quantify the cerebral OEF at different phases of stroke-like episodes in patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) by using MRI. METHODS We recruited 32 patients with MELAS confirmed by gene analysis. Conventional MRI scanning, as well as functional MRI including arterial spin labeling and oxygen extraction fraction im...
متن کاملQuantitative MRI of Cerebral Arterial Blood Volume
Baseline cerebral arterial blood volume (CBV(a)) and its change are important for potential diagnosis of vascular dysfunctions, the determination of functional reactivity, and the interpretation of BOLD fMRI. To quantitative measure baseline CBV(a) non-invasively, we developed arterial spin labeling methods with magnetization transfer (MT) or bipolar gradients by utilizing differential MT or di...
متن کاملQuantitative functional neuroimaging of cerebral physiology in healthy aging
Functional MRI (fMRI) studies using the BOLD signal are done under the general assumption that the BOLD signal can be used as a direct index of neuronal activation. Studies of cognitive aging often compare BOLD signal amplitude and extent directly between younger and older groups, with the additional assumption that the relationship between neuronal activity and the hemodynamic response is unch...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: NeuroImage
سال: 2012
ISSN: 1053-8119
DOI: 10.1016/j.neuroimage.2011.12.017